This article explains how the concept and the practice of gift-making evolved in Spanish Italy in connection with power. Contemporary chronicles, avvisi (newsletters), and letters enable us to reflect upon how gifts were seen, given, and received in the period at the Spanish embassy in Rome and in the viceroyalty of Naples. It aims to establish how the exchange of presents affected the wielding of power and how it contributed to shaping the political culture of the Spanish in Italy. The seventeenth century and Italy were the time and place that witnessed the greatest experimentation in gift-making practices. This experimentation and the polysemic nature of gifts can also be explained as a result of the low level of professionalization that still characterized diplomacy in seventeenth-century Europe.